Fig. 4

IFNAR deficiency reduces microgliosis following TBI. Microglial reactivity was visualized using IBA1 staining (green) 31 days following TBI. Representative IBA1 staining in the hippocampus (A and B) and thalamus (D and E) from injured WT and IFNAR KO mice. Scale bar = 200 μm. Quantification of % IBA1 area in thalamus (C and F). Error bars depict mean ± SEM. Statistical analysis performed by two-way ANOVA with Tukey’s test for multiple comparisons. *p < 0.05, n = 7–9 mice/group