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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: A heterozygous splicing variant IVS9-7A > T in intron 9 of the MAPT gene in a patient with right-temporal variant frontotemporal dementia with atypical 4 repeat tauopathy

Fig. 1

Clinical Images. a–d T1-weighted MR images at age 59. a Coronal image showing visible amygdala. Severe bilateral amygdala atrophy, predominantly on the right side, can be observed. White matter signal intensities in the left temporal lobe and right superior temporal gyrus are preserved, while those intensities in the right middle and inferior temporal gyri are attenuated. The third ventricle is enlarged. b Coronal image showing the hippocampal body. The hippocampus is mildly atrophic but relatively spared. c Axial image displaying predominantly enlarged right inferior horn of the lateral ventricle. Mild midbrain atrophy is noticeable. d Sagittal image revealing mild atrophy in the midbrain tegmentum area. e 3D-SSP image of 123I-IMP-SPECT demonstrates predominant right medial temporal hypoperfusion at age 57. f 123I-Ioflupane-SPECT reveals reduced binding to the striatal dopamine transporter, predominantly on the right side, at age 57

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Acta Neuropathologica Communications

ISSN: 2051-5960

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