Fig. 6
Increased VEGFA plasma levels in cSVD patients. (A) VEGFA blood plasma levels in cSVD patients were higher compared to age and sex-matched controls. (B) There was no correlation between VEGFA plasma levels and WMH volume in patients or controls. A trend in the relation between VEGFA plasma levels and leakage rate in (C) WMH and (D) NAWM in patients, but not in controls, was observed (indicated by the solid for patients and dotted line for controls). Abbreviations: WMH = white matter hyperintensities; NAWM = normal appearing white matter; Ki = leakage rate. For quantification, mean ± SEM; *p < 0.05; Mann–Whitney U-test