Fig. 5

BCAS led to an increase in BBB permeability after 7 days without changes in vascular density. (A) immunolabeling for lectin in the cortex, deep cortex, corpus callosum, and striatum. Scale bar, 50 µm. (B) Quantification of vessel density in BCAS compared to Sham. No statistical differences were found in vessel density when comparing BCAS to Sham in the respective areas. (C) Immunolabeling for blood vessel (Lectin), and mouse IgG for BBB leakages. Scale bar, 50 µm. (D) The number of leakages and (E) the total leakage size was significantly higher in BCAS compared to Sham. Mean ± SEM; **p < 0.01, vs Sham; unpaired student t-test