Table 4 Association of APOE-ε4 (rs429358) with different pathology contrasts

AD⁺LB⁺ vs. AD^–LB^–

4.24 [3.52 5.10] (1.49e-52)

3.86 [3.23 4.63] (5.10e-49)

5.02 [3.97 6.35] (2.21e-41)

12.6 [8.1 19.8] (2.1e-28)

2.31 [1.40 3.83] (1.1e-03)

4.25 [3.35 4.39] (1.29e-32)

N/A

AD⁺LB^– vs. AD^–LB^–

4.22 [3.60 4.96] (1.41e-69)

3.55 [3.07 4.12] (3.27e-64)

4.66 [3.87 5.60] (3.90e-60)

9.9 [6.4 15.3] (1.2e-24)

N/A

N/A

AD^–LB⁺ vs. AD^–LB^–

0.93 [0.60 1.43] (7.34e-01)

1.46 [1.12 1.90] (5.47e-03)

1.17 [0.74 1.84] (4.95e-01)

6.1 [3.5 10.5] (1.3e-10)

0.75 [0.43 1.30] (3.1e-01)

N/A

AD⁺LB⁺ vs. AD⁺LB^–

1.01 [0.90 1.13] (8.33e-01)

1.09 [0.97 1.22] (1.66e-01)

1.00 [0.88 1.14] (9.93e-01)

N/A

N/A

N/A

LB⁺ vs. AD^–LB^–

N/A

N/A

N/A

N/A

N/A

2.45 [2.22 2.74] (4.65e-63)

LB⁺ vs. LB^–

N/A

N/A

N/A

N/A

N/A

N/A

LB⁺ vs. AD^–LB⁺

N/A

N/A

N/A

N/A

N/A

N/A

AD⁺ vs. AD⁺LB^–

N/A

N/A

N/A

N/A

N/A

N/A

AD⁺LB⁺ vs. AD^–LB^–

N/A

N/A

N/A

1.88 [0.37 9.49] (4.5e−01)

3.42 [1.48 7.92] (4e−03)

3.74 [2.34 5.97] (4e−08)

9.37 [2.90 30.24] (2e−04)

5.58 [3.38 9.20] (2e−11)

6.96 [4.70 10.29] (3e−22)

N/A

N/A

N/A

AD⁺LB^– vs. AD^–LB^–

N/A

N/A

N/A

N/A

N/A

N/A

N/A

AD^–LB⁺ vs. AD^–LB^–

N/A

N/A

N/A

0.30 [0.10 0.87] (2.7e−02)

0.73 [0.40 1.34] (0.31)

3.46 [1.66 7.22] (1e−03)

N/A

N/A

N/A

AD⁺LB⁺ vs. AD⁺LB^–

N/A

N/A

(3e−02)

N/A

N/A

N/A

N/A

LB⁺ vs. AD^–LB^–

N/A

2.711 [2.313 3.177]

(7.09e−35)

N/A

N/A

2.40 [2.14 2.70]

(1.05e−48)

N/A

2.94 [2.34 3.71] (6.6e-20)

LB⁺ vs

LB^–

1.63 [1.52 1.76]

(2.8e-11)

N/A

N/A

N/A

N/A

N/A

N/A

LB⁺ vs. AD^–LB⁺

N/A

N/A

N/A

N/A

N/A

2.25 [0.25 19.90] (4.66e−01)

8.69 [0.70 107.39] (9.2e−01)

9.32 [2.12 40.95] (3e−03)

N/A

AD⁺ vs. AD⁺LB^–

N/A

N/A

N/A

N/A

N/A

0.71 [0.17 2.95] (6.4e−01)

0.93 [0.48 1.82] (8.3e−01)

N/A