Fig. 1

Methylation pattern of long-term and short-term survivors of glioblastoma. The mean ± SEM of relative percentage of methylation from all long-term and all short-term survivors of glioblastoma per CpG of MGMT reveals differences between these groups. Whereas glioblastoma samples of long-term survivors demonstrate frequently methylation in areas CpGs 28–40 and CpGs 75–96, those areas in neoplasms of short-term survivors are mainly unmethylated. The connecting line is added for visualization purposes