Table 3 Performance of the prognostic models comprised of various 5hmC and transcriptomic features
Data | 5hmC | Transcriptome | 5hmC-Transcriptome | ||
|---|---|---|---|---|---|
Feature type | Promoter | H3K27ac | Gene body | mRNA | Integrated |
Model | Glmboost | Glmnet | Glmboost | Glmboost | Glmboost |
Feature Selection Method | rf | uc | rf | rf | rf |
Feature Number | 30 | 20 | 20 | 10 | 30 |
IDH1 | 0.57 (0.47–0.67) | ||||
Age + Gender + IDH1 | 0.68 (0.53–0.83) | ||||
PS | 0.74 (0.60–0.87) | 0.72 (0.58–0.86) | 0.69 (0.53–0.85) | 0.70 (0.56–0.85) | 0.74 (0.60–0.88) |
Age + Gender + PS | 0.74 (0.61–0.87) | 0.70 (0.58–0.83) | 0.70 (0.57–0.83) | 0.72 (0.58–0.85) | 0.71 (0.57–0.86) |
Age + Gender + IDH1 + PS | 0.72 (0.59–0.86) | 0.69 (0.55–0.84) | 0.68 (0.54–0.83) | 0.72 (0.59–0.85) | 0.72 (0.58–0.86) |