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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: The specific DNA methylation landscape in focal cortical dysplasia ILAE type 3D

Fig. 2

Differential promoter methylation of mir-124-3 in FCD 3D with loss of layer 4. The figure summarizes from top to bottom the genomic environment of the mir-124-3 gene with strand specificity on chromosome 20, gene regulatory features based on ENSEMBL annotations, including putative promoter and enhancer regions, and increased promoter methylation in FCD 3D with loss of layer 4. Leading edge indicates CpGs with significant and uniform methylation change (here increase) in green upstream of the transcriptional start site of miR-124-3. CpGs not considered are marked in red

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