Fig. 1

a:UMAP and b:hierarchical cluster analysis of FCD 3D subgroups together with FCD 2A/B, 1A, TLE, and autopsy controls. Histologically defined FCD 3D subgroups form separate and distinct methylation classes. c: Reactome and d: KEGG pathway enrichment of differentially methylated CpGs in FCD 3D subgroups. Each color represents a particular group, while a connection indicates whether a pathway is enriched. Pathways with two or more connections are enriched for two or more groups. The color scheme for histopathological entities in 1a also applies to 1b-d