Fig. 4

Quantification of DLF vascular branching and coverage in cases without CAA. Differences between groups were established by ANCOVA with means adjusted for evaluation at mean age of death = 61.4 years. The gray matter branch density and fraction volume ratios were calculated by dividing the branch density or fraction volume of the sulcus by the branch density or fraction volume of the crest. a vessel fraction volume in the gray matter sulcus, b vessel branch density in the gray matter sulcus, c gray matter fraction volume ratio, and d gray matter branch density ratio. *p < 0.05, **p < 0.01, ***p < 0.001. CTE n = 17, controls n = 13