Fig. 3

Quantification of DLF vascular branching and coverage. Differences between groups were established by ANCOVA with means adjusted for evaluation at mean age of death = 64.2 years and CAA = 0.3659. The gray matter branch density and fraction volume ratios were calculated by dividing the branch density or fraction volume of the sulcus by the branch density or fraction volume of the crest. a Gray matter sulcus branch density, b Gray matter branch density ratio c Gray matter fraction volume ratio. *p < 0.05, **p < 0.01, ***p < 0.001. CTE n = 25, controls n = 15