Skip to main content
Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: DNA methylation, combined with RNA sequencing, provide novel insight into molecular classification of chordomas and their microenvironment

Fig. 6

Validation of the study findings in an independent data set (GSE205331) [14] (a) Clustering the samples with a set of 10 010 array probes (variable probes from both experiments, occurring in both EPIC and HM450K arrays) with heatmap of scaled methylation M-values (b) Beta-values of probes with standard deviation of β-values above 0.1, split according to CpG relation to CGI (c) Difference in the methylation levels of cg12044599 CpG in PTPRCAP locus in chordoma C and I subtypes in samples from current study, validation data set and in metaclusters (d) Difference in the content of CD8+ lymphocytes in chordoma C and I subtypes from current of study group, validation data set and in metaclusters

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us