Fig. 2
From: The contribution of DNA methylation to the (dys)function of oligodendroglia in neurodegeneration
Schematic of the myelin changes throughout life. Shaded areas indicating myelination waves (as defined by de Faria et al. [29]). Also depicted are visualizations of the progression of cortical myelination and the progression of Alzheimer’s disease related destruction. The average age of onset of multiple neurodegenerative diseases is also indicated and coincides with the start of normal ageing-related decline in myelination, which is hypothesized to be accelerated in neurodegeneration. Figure created with BioRender