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Fig. 10 | Acta Neuropathologica Communications

Fig. 10

From: Alterations in iron content, iron-regulatory proteins and behaviour without tau pathology at one year following repetitive mild traumatic brain injury

Fig. 10

Assessment of gait in mice following single or r-mTBI. Gait deficits assessed using DigiGait following five impacts at 1, 3, 6, 9 and 12 months post-injury. A Swing is significantly increased at 9 months following 5x TBI compared to Shams. B %SwingStride is significantly increased at 9 months following 5x TBI compared to Shams. C Significant increase in midline distance at 9 and 12 months following 5x TBI versus Shams. D %PropelStride is significantly decreased at 9 and 12 months following 5x TBI versus Shams. E Significant increase in stance width at 9 months following 5x TBI compared to Shams. Mixed-effects analysis and uncorrected Fisher’s LSD post-hoc. Data expressed as mean ± SEM, *P < 0.05, **P < 0.01, n = 9–10 (Sham), n = 8–10 (TBI), * indicates a significant difference between TBI and Sham animals at a specific time point

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Acta Neuropathologica Communications

ISSN: 2051-5960

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