Table 1 Demographic and clinical data for healthy controls and patients

Demographical variables

Age (years)

40.9 (9.8)

47.5 (10.1)

t₍₈₁₎ = 2.957

p = 0.004*

Education (no post-secondary educ./apprenticeship only/attended college or higher)

1/20/14

4/27/17

Z = 3.766

p = 0.288

Substance use patterns

Ethanol (g/day; mean of last 90 days)

6.1 (5.7)

202.5 (196.8)

t₍₈₁₎ = 5.809

p < 0.001*

ADS (total score)

2.12 (2.4)

15.31 (6.8)

t₍₇₉₎ = -10.744

p < 0.001*

Abstinence before MRI scan (days)

-

12.52 (7.8)

-

-

Smoking (yes/no)

3:31

32:16

Chi²₍₁₎ = 25.495

p < 0.001*

Cigarettes per day in smokers (0–10/ 11–20/ 21–30/ >30)

1/0/2/0

2/8/14/8

Chi²₍₆₎ = 4.162

p = 0.210

FTND in smokers (total score)

5.3 (4.6)

6.1 (2.1)

t₍₃₃₎ = 0.558

p = 0.581

Clinical scales

OCDS (total score)

1.53 (1.3)

16.85 (7.7)

t₍₇₈₎ = -11.178

p < 0.001*

BDI

2.09 (2.6)

17.20 (11.4)

t₍₈₁₎ = -6.144

p < 0.001*

STAI

30.62 (7.0)

45.92 (13.2)

t₍₇₉₎ = -7.574

p < 0.001*