Fig. 4

Chronic intermittent ethanol exposure increased hippocampal excitability. A, B. PS amplitudes and EPSP slopes, respectively, recorded in the DG in response to perforant path stimulation of increasing intensities in PD (orange) and control (black) rats. C. Input (EPSP) - output (PS) curves in the DG. Data was fitted with a logarithmic regression. No differences were found between both curves. D, E. Same as A, B but recorded in the CA1 in response to fimbria stimulation. F. Same as C for the CA1 responses. Data are fitted with linear regressions. Both curves are significantly different (extra sum-of-squares F test: F_(2,8) = 69,87, p-value < 0,0001). The asterisk represents significant difference in the two-way repeated-measures ANOVA for PD vs. control groups (*p < 0.05)