Fig. 2

Effects of chronic alcohol exposure in dw-MRI parameters measured in the fimbria/fornix. (A, B) Representative DTI reconstruction of the fimbria/fornix in native space for one control rat (A) and one post-dependent rat (B). Both representations are displayed using DTI color conventions, superimposed on the FA maps. (C, D). Group-level values of fractional anisotropy (n = 16 control rats; 15 PD rats) (C) and myelin fraction (n = 15 control rats; 15 PD rats) (D) in the fimbria/fornix are shown for control and PD rats. Box-and-whisker plot showing the first and third quartile (box) and min/max values (whiskers). The horizontal line in the box represents the median. The asterisk represents significant difference in the unpaired t-test statistic (*p < 0.05)