Fig. 1

Timeline of the cuprizone administration and myelination state in Abcd1 KO and WT mice. (a) Schematic depicting the cuprizone-feeding paradigm used in the study, along with the corresponding time points for analysis. (b) Evaluation of the extent of demyelination and remyelination in the corpus callosum based on LFB/PAS myelin staining (subjective score: 0, complete myelination; 3, complete demyelination). The graph shows group means ± SEM (controls: n = 5 WT, 4 Abcd1 KO; treatment time points: n = 6–10 WT, 6–9 Abcd1 KO mice). The individual values are displayed in Additional file 2:  Fig. S2b