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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Mass cytometric analysis of the immune cell landscape after traumatic brain injury elucidates the role of complement and complement receptors in neurologic outcomes

Fig. 4

Complement inhibition improves histological and cognitive outcomes. A Brain lesion volume at day 28 after TBI in PBS vs CR2-Crry treated groups measured using MRI. B Barnes maze performance in week 3 after TBI in PBS vs CR2-Crry treated groups. C Performance on the retention day of the Barnes maze showing individual data points. Data are shown as mean ± SEM. N = 9 per group. Tissue samples were taken from 6 randomly chosen animals for the CyTOF analysis. Significance was calculated in A using unpaired t-test and in B-C using 1-way Anova with Bonferroni post-test (*p < 0.05, ***p < 0.001)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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