Skip to main content
Fig. 10 | Acta Neuropathologica Communications

Fig. 10

From: Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

Fig. 10

Comparison of Aβ proteoform ratios in cell media from APP WT and APP FAD mutants. The ratios of A Aβ1-42/Aβ1-40, B Aβ1-38/Aβ1-40 (C) Aβ1-38/Aβ1-42 and (D) Aβ1-17/Aβ1-40 were compared between APP WT and the FAD mutant HEK293T cells. The circles represent the two biological replicates (N = 2), each of which are the averaged technical replicates from MALDI-TOF. For comparing sample types, a one-way ANOVA with Tukey’s post hoc test was conducted (*p < 0.05, **p < 0.01, ****p < 0.0001)

Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us