Fig. 1
From: Rise and fall of peroxisomes during Alzheimer´s disease: a pilot study in human brains
Immunohistochemical detection of Aβ including neuritic plaques and NFTs to classify the human brain samples to patients with no, low, mid and high ADNC. Light microscopy images of Aβ deposits (4G8, a-f), NFTs (AT8, g-l) and neuritic plaques (4G8-positive plaques with a dense core accompanied by AT8-positive abnormal neurites) in the frontal neocortex (CF), and hippocampal CA3 region (CA3). Whereas high amounts of Aβ (m) and NFTs (not shown) were found in the subiculum of patients with high ADNC, a high density of NTFs (n), in the absence of Aβ (o) was found in the subiculum (Sub) of the patient with tauopathy