Fig. 3

Immunohistochemical detection of SARS-CoV-2. Immunohistochemical detection of SARS-CoV-2 using antibodies targeting nucleocapsid (A, E, C, G) and spike proteins (B, F, D, H). Left panels showing brain regions (A-B left stereoanterior, E–F right stereoanterior); right panels showing lung regions (C, D, G, H). One representative COVID-19 case per line: Case 2 (A-D) and Case 10 (E–H). Case 2: No viral proteins were detected in the brain parenchyma A, B) while viral proteins were detected in the lung (C, D). Case 10: viral proteins were detected near some brain capillaries (arrows) (E, F) while viral proteins were not detected in the lung (G, H). Brain, Scale bar = 50 µm; Lung, Scale bar = 100 µm