Fig. 3
From: Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease
Sex stratified analyses identified several female specific signals. A Manhattan plot showing the p-values in the 5195 female and 4625 male participants across 9 cohorts. The blue and red lines represent the suggestive (P = 1 × 10−5) and genome-wide significance thresholds (P = 5 × 10−8). Variants with a p value below 1 × 10−15 are not shown. The observed genomic control value (λ) was 1 for both strata. Local Manhattan plot showing the genome-wide significant locus from the chr5 (B) and chr11 (C) for female-specific signals. The relative location of genes and the direction of transcription are shown in the lower portion of the locus zoom plots