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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease

Fig. 2

Multi-ethnic meta-analysis (N = 13,409) identified novel signals in chr 1, 14, and 19 associated with brain amyloidosis. A Manhattan plot showing the p-values in the multi-ethnic meta-analysis. The blue and red lines represent the suggestive (P = 1 × 10−5) and genome-wide significance thresholds (P = 5 × 10−8). Variants with a p value below 1 × 10−15 are not shown. Local Manhattan plot for the chr1 (B), chr14 (C), and chr19 (D, E) loci. The relative location of genes and the direction of transcription are shown in the lower portion of the locus zoom plots

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