Fig. 3
From: ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics
ER and UPR associated proteins in arterioles in CADASIL subjects. A-H, Representative images of the same blood vessel in the WM stained with antibodies to GRP/BiP78 (A), Erp72 (B), Rab6 (C), HSP70 (D), HSP27 (E), and Calnexin (F) in a CADASIL case and for Erp72 (G) and Calnexin (H) in similar age control. Mostly punctate immunoreactivity was evident in the arteriole wall in CADASIL, most marked for HSP27. Scale bar represents 150 μm (A-H)