Fig. 2
From: ER stress induced immunopathology involving complement in CADASIL: implications for therapeutics
Heat map plots showing grouped categories of proteins with significant de-regulation differences in CADASIL versus YC. A, Proteins implicated in endoplasmic reticulum stress responses. B, Proteins implicated in cell cycle and/or nuclear responses. C, Proteins of the cerebral mitochondria proteome. D, Proteins implicated in cellular calcium homeostasis. E, Proteins implicated in antioxidant and oxidant responses. F, Proteins implicated in synaptic transmission, including ion channels and structural synaptic markers. G, Proteins implicated in cytoskeleteon-related intracellular dynamics. H, Proteins implicated in glycolysis. I, Proteins implicated in cellular structural functions and cytoskeleton. J, Proteins acting as integrins, ligands and inflammatory markers. K, Proteins of the extracellular matrix. L, Uncategorized proteins for the rest of the referred molecular and functional categorizations. All categorizations were based on specific proteomics categorization applications including FunRich, Panther and DAVID open software