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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Clinicopathological and molecular characterization of a case classified by DNA‑methylation profiling as “CNS embryonal tumor with BRD4–LEUTX fusion”

Fig. 3

Immunohistochemical features. a Diffuse Synaptophysin immunopositivity (magnification 400×). b Diffuse CD56 immunopositivity (magnification 400×). c Intense nuclear immunopositivity of p53 protein in more than 10% of the tumoral cells (magnification 400×). d Loss of Filamine-A expression in tumoral cells with immunopositivity in endothelial cells (magnification 400×). e Loss of H3K27me3 expression in tumoral cells with immunopositivity in endothelial cells (magnification 400×). f High KI-67 proliferation index with some hotspot of more than 50% of immunopositivity in tumoral cells (magnification 200×)

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Acta Neuropathologica Communications

ISSN: 2051-5960

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