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Fig. 7 | Acta Neuropathologica Communications

Fig. 7

From: Human tau-overexpressing mice recapitulate brainstem involvement and neuropsychiatric features of early Alzheimer’s disease

Fig. 7

Hyperphosphorylated tau and altered expression of TPH2, TH, IDO1, and TGM2 protein levels in the monoaminergic nuclei. A Atlas plate indicating the DRN region that was dissected for Western blot analysis. Representative western blot images showing the B HT7 and AH36 C TPH2 D IDO1 E TGM2 protein levels in the DRN of C57BL/6 J and htau +/- . F Atlas plate indicating the LC region that was dissected for Western blot analysis. Representative western blot images showing the G HT7 and AH36 H TH I IDO1 J TGM2 protein levels in the LC of C57BL/6 J and htau ± . *p < 0.05, **p < 0.01

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