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Table 1 Clinical characteristics of brain metastasis from lung and breast cancer

From: Tumor lineage-specific immune response in brain metastatic disease: opportunities for targeted immunotherapy regimen?

Characteristics

No

%

Total samples

22

100

Cancer type

  

Brain metastasis from lung adenocarcinoma

11

50

Brain metastasis from breast cancer

11

50

Lung cancer

Median age at diagnosis, years (range)

64 (46–74)

 

Sex

 Male

6

54.5

 Female

5

45.5

Histology

 Adenocarcinoma

11

100

Smoking status

 Never smoking

1

9.1

 Former smoker

5

45.5

 Smoking

4

36.4

 Unknown

1

9.1

Treatment after surgery of BM

 No treatment

1

9.1

 Radiotherapy

6

54.4

 SRT

1

9.1

 WBRT

2

18.2

 Other

1

9.1

Breast cancer

Median age at diagnosis, years (range)

48 (36–74)

 

Histology of primary tumor

 ER/PR + 

2

18.2

 ER/HER2 + 

1

9.1

 HER2 + 

1

9.1

 TNBC

5

45.5

 Unknown

2

18.2

Histology of matched-BM

 ER + 

3

16.7

 PR + 

2

11.1

 ER/PR + 

1

5.6

 HER2 + 

2

11.1

 TNBC

2

11.1

Unknown

1

5.6

Treatment after surgery of BM

 Radiotherapy

5

45.5

 Chemotherapy

2

18.2

 Radiotherapy & Chemotherapy

2

18.2

 Other

2

18.2

  1. ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor 2; TNBC: triple-negative breast cancer; SRT: Stereotactic radiotherapy; WBRT: Whole brain radiotherapy