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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Cell-specific vulnerability to metabolic failure: the crucial role of parvalbumin expressing neurons in creatine transporter deficiency

Fig. 3

GO analysis for biological process from the snRNA-seq dataset in neuronal clusters. a-d Fold enrichment of top-level overrepresented GO terms in excitatory (a,b) and inhibitory (c,d) neurons from CrT+/y (n = 2) and CrT−/y (n = 2) animals showing enrichment in synaptic pathways. Calculated by ShinyGO 0.76.3, FDR < 0.05. e,f Hierarchical dendrograms of synaptic proteins corresponding to DEGs (SynGO database) identified in the same animals showing significant enrichment by color code: (e) excitatory neurons (f) inhibitory neurons

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Acta Neuropathologica Communications

ISSN: 2051-5960

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