Table 1 Clinical characteristics of the studied cohort of patients with primary diffuse IDH-mutant gliomas (n = 37)

Gender

 Female

15 (40.5)

 Ratio male:female

1.5

Age at diagnosis—years

 Mean ± SD

38.1 ± 11.5

Tumor location

 Frontal

23 (62.2)

 Insular

2 (5.4)

 Occipital

1 (2.7)

 Parietal

5 (13.5)

 Temporal

6 (16.2)

Recurrence location in relation to primary tumor

 Local

36 (97.3)

 Distant

1 (2.7)

Histomolecular reclassification of primary tumors (2021 WHO CNS criteria)

 Astrocytoma, IDH-mutant CNS WHO grade 2

12 (32.4)

 Astrocytoma, IDH-mutant CNS WHO grade 3

11 (29.7)

 Astrocytoma, IDH-mutant CNS WHO grade 4

2 (5.4)

 Oligodendroglioma, IDH-mutant and 1p/19q-codeleted, CNS WHO grade 2

10 (27.0)

 Oligodendroglioma, IDH-mutant and 1p/19q-codeleted, CNS WHO grade 3

2 (5.4)