Fig. 4
From: Clinico-pathological and epigenetic heterogeneity of diffuse gliomas with FGFR3::TACC3 fusion
Unsupervised hierarchical clustering of DNA-methylation profiling data. Unsupervised hierarchical clustering of 23 glioma samples with FGFR3:TACC3 fusion based on the 10,000 most variably methylated probes. Samples with CS > 0.9 were considered as matching with the MC proposed by the v12.5 version of the DKFZ classifier, CS ≤ 0.9 were considered not matching. Chr chromosome, DNET dysembryoplastic neuroepithelial tumor, GG ganglioglioma, IHG infantile hemispheric glioma, LGG low grade glioma, GB IDH-WT glioblastoma IDH-wildtype, GB_MES_TYP glioblastoma mesenchymal subtype, GB_RTK2 glioblastoma RTK2 subtype, MYXGNT, PDGFRA-mutant (novel) Myxoid glioneuronal tumor, PDGFRA-mutant (novel), RGNT rosette forming glioneuronal tumor