Fig. 6

Injury-induced Ctgf production is driven by H₂O₂. A Longitudinal view of whole mount preparations of sciatic nerves four days after nerve crush in the absence (upper panels) or presence (lower panels) of catalase delivered intra-sciatically. Ctgf is in pseudocolors  and SCs are GFP-positive (green). Scale bars: 100 µm. B Cross-sections of sciatic nerves four days after nerve compression in the absence (upper panels) or presence (lower panels) of catalase delivered via intra-nerve injection. SCs are GFP-positive, NF are in white and Ctgf is in pseudocolors. A pseudocolor scale is added in the corresponding figures, where white corresponds to the highest intensity, and black to the lowest. Scale bars: 100 µm. Quantification of Ctgf signal in cross-sections is shown in C. N = 4, *p = 0.012