Fig. 8

Abundant Aβ aggregates are stained by Amylo-Glo dye in AD-like degu brain. a Fluorescent microscopic images show Aβ plaques in a coronal section with hippocampus from an AD-like degu brain stained with Amylo-Glo fluorescent dye. b, c a higher magnified view of boxed areas in a shows Aβ plaques (arrows) in both hippocampus (hippo) and cortex areas. d–f A confocal microscopic view of hippocampal CA1 Aβ plaques (d), a large cluster of plaques in the cortical area (e), and several vascular structures within hippocampus. (g, h) A representative view of Amylo-Glo-stained coronal brain slices of 5xFAD mice shows Aβ plaques (arrows) in the cortex and hippocampus areas