Fig. 4

Quantification of Lewy body-like phospho-Serine-129 positive αSyn pathology in the SNpc. Representative images of αSyn pathology in dopaminergic neurons present in the SNpc ipsilateral to PFF injection (A₁–B₃). αSyn pathology is not present in monomeric αSyn injected into the SNpc and sham rat SNpc (C₁–D₃). Quantification of αSyn aggregates in rats that underwent either 4 or 8 r-mTBIs compared to their controls (E₁–E₂). αSyn pathology is present in the SNpc ipsilateral to the PFF injection (F₁) and not on the contralateral side (F₂). White arrowheads indicate authentic, Lewy Body-like inclusions localized to TH+ dopaminergic neurons in the SNpc (A₂–A₃, B₂–B₃)