Table 1 Characteristics of study participants
From: Methylation differences in Alzheimer’s disease neuropathologic change in the aged human brain
Demographics | AD neuropathologies | Copathologies | ||||||
|---|---|---|---|---|---|---|---|---|
Sex | AD severity score | Braak lewy body staging | ||||||
Male | 12 (25.53%) | Not | 2 (4.26%) | 0 | 31 (65.96%) | |||
Female | 35 (74.47%) | Low | 2 (4.26%) | 1 | 4 (8.51%) | |||
Age at death | Intermediate | 15 (31.91%) | 2 | 1 (2.13%) | ||||
Mean (SD) | 97 (± 3.5) | High | 28 (59.57%) | 3 | 3 (6.38%) | |||
Education | NIA-AA A score | 4 | 0 (0.0%) | |||||
Not college | 21 (44.68%) | 0 | 2 (4.26%) | 5 | 2 (4.26%) | |||
Minimum college | 26 (55.32%) | 1 | 4 (8.51%) | 6 | 6 (12.77%) | |||
Clinical diagnosis | 2 | 6 (12.77%) | TDP-43 | |||||
Normal | 19 (40.43%) | 3 | 35 (74.47%) | 0 | 29 (61.70%) | |||
CIND | 15 (31.91%) | NIA-AA B score | 1 | 4 (8.51%) | ||||
Dementia | 13 (27.66%) | 2 | 17 (36.17%) | 2 | 12 (25.53%) | |||
APOE genotype | 3 | 30 (63.83%) | 3 | 2 (4.26%) | ||||
2,3 | 5 (10.94%) | NIA-AA C score | MVL burden | |||||
2,4 | 3 (6.38%) | 0 | 3 (6.38%) | 0 | 38 (80.85%) | |||
3,3 | 24 (51.06%) | 1 | 4 (8.51%) | 1 | 5 (10.64%) | |||
3,4 | 5 (10.64%) | 2 | 8 (17.02%) | 2 | 1 (2.13%) | |||
Missing | 10 (21.3%) | 3 | 32 (68.09%) | 3 | 3 (6.38%) | |||