Fig. 4
From: Stem cell phenotype predicts therapeutic response in glioblastomas with MGMT promoter methylation
The raw counts of cells in individual fields of all tumors quantified by immunofluorescence are shown A, and show a weak tendency for more cellular areas to have more SOX2-positive cells. The coefficient of variation (SD/Mean) for each case B shows a strong tendency for higher variability in cases with a low mean percentage of SOX2-positive cells. Using the median cut-off of 30% for percent of SOX2-positive cells by immunofluorescence, the mean variance is 93.5% in the low-expressing group and 25.1% in the high-expressing group (p < 0.002)