Fig. 4

Relationship between NFT counts by region and each individual cognitive variable. In this analysis we used a loose label of cognitive impairment as a composite metric based on MMSE, CDR, or documented clinical history of cognitive impairment. This figure shows the relationships between AI-detected NFT counts by region and each individual clinical variable. (Left column) Two-sample t-tests were performed for documented clinical history of cognitive impairment. (Middle column) Spearman rho correlation was performed between NFT count and CDR score. (Right column) Pearson r correlation was performed between NFT count and MMSE