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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Human induced pluripotent stem cell engineering establishes a humanized mouse platform for pediatric low-grade glioma modeling

Fig. 6

Pediatric LGG cells form lesions in Rag1−/− and Cxcl10−/− mice a and b Representative images of H&E, Ki67, GFAP and OLIG2 staining of pediatric LGG tumors in Rag1−/− (top) and Cxcl10−/− (bottom) mice at 1mpi and 6mpi using two pediatric LGG lines: JHH-NF-PA (a) and Res186 (b). The number of LGG-bearing mice is indicated within the H&E panels. Bar graphs denote the % Ki67+ cells in the lesions. Data are represented as means ± SEM. Scale bars: left H&E panel, 1 mm; other panels, 100 µm

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