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Fig. 1 | Acta Neuropathologica Communications

Fig. 1

From: Focal amyloid and asymmetric tau in an imaging-to-autopsy case of clinical primary progressive aphasia with Alzheimer disease neuropathology

Fig. 1

Progression of atrophy. Structural T1-weighted MRI derived cortical thickness differences between the primary progressive aphasia (PPA) participant and 35 normal controls (NC). The z-score map displays vertices greater than 2 standard deviations from the mean of the NC group. Warmer colors indicate less cortical thickness for the PPA participant. Left perisylvian temporal cortex, middle frontal cortex, and supplementary motor regions are the most abnormal early in disease course. A rapid progression of cortical thinning is detectable at each subsequent visit, with greater involvement of left hemisphere regions

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Acta Neuropathologica Communications

ISSN: 2051-5960

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