Fig. 5

Visual demonstration and internal consistency of the third CNN. A Shown is a specimen slide from the surgical approach, close to the tumor margin of a non-small cell lung cancer metastasis, with three random areas (A, B, C). B Digital H&E-like images A–C. C Visualization of prediction heatmaps for each output class. D Shown are the overlaying heatmaps with the largest and correctly calculated green area part for non-tumorous tissue (white matter). The asterisk and arrow in the middle image demonstrate small non-significant differences at patch size level between random areas. Scale bars = 100 μm