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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: The dural angioleiomyoma harbors frequent GJA4 mutation and a distinct DNA methylation profile

Fig. 4

t-distributed stochastic neighbor embedding (t-SNE) analysis of DNA methylation profiles of the six investigated tumors alongside selected reference samples. Reference DNA methylation classes: angiomatoid fibrous histiocytoma (AFH), angioleiomyoma/myopericytoma (ALM_MYP), angiosarcoma (ANGIOSARC), arteriovenous malformation (AVM), chordoma (CHORDM), central nervous system neuroblastoma, FOXR2-activated (CNS_NB_FOXR2), epithelioid hemangioendothelioma (EH), Ewing sarcoma (EWS), high grade neuroepithelial tumor with BCOR alteration (HGNET_BCOR), high grade neuroepithelial tumor, with MN1 alteration (HGNET_MN1), hemangioblastoma (HMB), inflammatory myofibroblastic tumor (IMPT), meningioma (MNG), and solitary fibrous tumor/hemangiopericytoma (SFT_HMPC). The cases #1, 2, 3, 6, and 7 clustered together and were separated from other DNA methylation classes

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