Table 4 Semi-quantitative analysis of immunohistochemical data with PDGFR-ɑ and Olig2 antibodies
From: Oligodendrocyte lineage is severely affected in human alcohol-exposed foetuses
Term | FASD/Ctrl | GE | CP | ||
|---|---|---|---|---|---|
PDGFR-ɑ | Olig2 | PDGFR-ɑ | Olig2 | ||
15 WG | FASD | 30%+++ | 40%+++ | 20%++ | 30%+++ |
16 WG | CTRL | 60%++++ | 60%++++ | > 60%++++ | 80%++++ |
20 WG | FASD | 80%++++ | 30%+++ | 60%++++ | 20%++ |
CTRL | 20%++ | 40%+++ | 40%+++ | 40%+++ | |
22 WG | FASD 1 | 70%++++ | 10%+ | 60%++++ | 5%+ |
FASD 2 | 60%++++ | 10%+ | 50%+++ | 5%+ | |
CTRL | 30%+++ | 50%++++ | 40%+++ | 40%+++ | |
24 WG | FASD 1 | 60%++++ | 2%+ | 40%+++ | 1%+ |
FASD 2 | 80%++++ | 30%++ | 40%+++ | 10%+ | |
CTRL | 10%+ | 10%+ | 30%+++ | 40%+++ | |
26 WG | FASD 1 | 60%++++ | 20%++ | 50%+++ | 30%+++ |
FASD 2 | 60%++++ | NA | 40%+++ | 5%+ | |
CTRL | 5%+ | 5%+ | 30%+++ | 35%+++ | |
29 WG | FASD | 70%++++ | 5%+ | 60%++++ | 5%+ |
28 WG | CTRL | 20%++ | 20%++ | 50%+++ | 20%++ |
30 WG | FASD | 80%++++ | 20%++ | 60%++++ | 5%+ |
CTRL | 20%++ | 10%+ | 40%+++ | 40%+++ | |
31 WG | FASD 1 | 30%+++ | 10%+ | 60%++++ | 3%+ |
FASD 2 | 30%+++ | 5%+ | 50%+++ | 1%+ | |
32 WG | CTRL | 20%++ | 10%+ | 40%+++ | 20%++ |
33 WG | FASD | Absent | Absent | > 60%++++ | 5%+ |
34 WG | CTRL | Absent | Absent | 50%+++ | 20%++ |
37 WG | FASD | Absent | Absent | 60%++++ | 1%+ |
36 WG | CTRL | Absent | Absent | 40%+++ | 30%+++ |