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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Changes in glial cell phenotypes precede overt neurofibrillary tangle formation, correlate with markers of cortical cell damage, and predict cognitive status of individuals at Braak III-IV stages

Fig. 5

Number of CD68 + microglia was significantly higher in the temporal pole and visual cortex of demented but not in resilient when compared to control brains (a). A similar trend that did not reach statistical significance was observed in the number of HLA-DR + microglia (a). Representative photomicrographs of CD68 + and HLD-DR + microglia on sections from control, resilient and demented cases containing temporal pole are displayed on the right (b). C Control (Braak 0-II); R Resilient (Braak III/IV); D Demented (Braak III/IV); *p < 0.05; **p < 0.01; ****p < 0.0001. Scale bars 50 μm

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Acta Neuropathologica Communications

ISSN: 2051-5960

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