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Table 3 Status of NMJs analyzed by confocal microscopy per donor biopsy

From: Impaired signaling for neuromuscular synaptic maintenance is a feature of Motor Neuron Disease

Donor ID and disease status Fully Innervated (%) of total NMJs/Donor Partially denervated-reinnervated (%) of total NMJs/Donor Denervated (%) of total NMJs/Donor
Con-1 2/2 NMJs (100%) 0/2 NMJs 0/2
Con-2 12/12 NMJs (100%) 0/12 NMJs 0/12
Con-3 17/19 NMJs (89%) 2/19 NMJs (11%) 0/19
Con-4 20/22NMJs (90%) 2/22 NMJs (10%)  
Con-5 10/12 NMJs (83%) 2/12 NMJs (17%) 0/12
Con NMJ Mean % 92.4% 7.6% 0%
MND-2 4/13 NMJs (30%) 9/13 NMJs (70%) 0/13 NMJs
MND-3 5/40 (12%) 20/40 (50%) 15/40 NMJs (38%)
MND-4 0/24 (0%) 20/24 (83%) 4/24 (17%)
MND NMJ Mean % 14% 67% 18%
  1. NMJ status is expressed as a fraction of classified NMJ over the total number of NMJs analyzed per donor muscle biopsy