Skip to main content

Table 2 Performance of each tau antibody in consensus reporting of CTE-NC as absent or present

From: Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change

 

AUC (95% CI)

Sensitivity %

Specificity %

PPV %

NPV %

All sections

0.74

(0.70–0.77)

57.9

86.1

92.6

40.5

PHF-1

0.85

(0.79–0.92)

80.6

86.1

94.6

59.6

4R

0.82

(0.74–0.89)

73.0

83.0

92.9

50.8

GT-38

0.75

(0.70–0.80)

51.9

97.2

98.2

40.2

3R

0.52

(0.46–0.59)

15.7

88.9

81.0

26.0

  1. AUC = area under the curve; PPV = positive predictive value; NPV = negative predictive value; GT38 vs. 4R, p = 0.140; GT38 vs. PHF-1, p < 0.005; 4R vs. PHF-1, p = 0.375; 3R vs. PHF-1, p < 0.001
Back to article page

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us