Fig. 3
From: Insulin-like growth factor 5 associates with human Aß plaques and promotes cognitive impairment
Physical exercise improves spatial reference memory in the Y-maze test of young mice. a Diagram for spontaneous alternations in the Y-Maze test. b Diagram of entries and distances to the known and unknown arm in the Y-Maze. c Quantification of spontaneous alternation between 3-month-old WTSed, WTRun, Bp5 tg + Sed and Bp5 tg + Run mice. d, e Quantification of spatial reference memory in 3-month-old WTSed, WTRun, Bp5 tg + Sed and Bp5 tg + Run mice by analysing the number of arm entries (d) and distance travelled (e) into known versus unknown arm after entering the maze. f Quantification of spontaneous alternation between 18-month-old WTSed, WTRun, Bp5 tg + Sed and Bp5 tg + Run mice. g, h Quantification of spatial reference memory in 18-month-old WTSed, WTRun, Bp5 tg + Sed and Bp5 tg + Run mice by analysing the number of arm entries (g) and distance travelled (h) into known versus unknown arm after entering the maze. Data represent mean ± SD, Kruskal–Wallis test, Dunn's post hoc test; *p < 0.05, **p < 0.01, ***p < 0.001; n = number of mice