|
Characteristic
|
MES
|
RTK I
|
RTK II
|
GBM classification
|
Study
|
GBM Class x Study
|
|---|
|
Mean (sd)
|
Mean (sd)
|
Mean (sd)
|
*F-value
|
Pr(> F)
|
*F-value
|
Pr(> F)
|
*F-value
|
Pr(> F)
|
|---|
|
Patient age [yrs]
|
60.175 (10.853)
|
61.075 (11.927)
|
60.834 (10.83)
|
0.216
|
0.806
|
52.158
|
< 0.001
|
0.747
|
0.612
|
|
DNAm age [yrs]
|
89.246 (21.746)
|
94.538 (24.999)
|
104.106 (26.163)
|
10.717
|
< 0.001
|
4.670
|
0.003
|
1.896
|
0.079
|
|
Age accel [yrs]
|
29.072 (19.566)
|
33.463 (21.956)
|
43.273 (25.652)
|
10.480
|
< 0.001
|
1.457
|
0.225
|
2.456
|
0.024
|
|
HM-purity
|
0.592 (0.104)
|
0.817 (0.105)
|
0.802 (0.099)
|
68.162
|
< 0.001
|
2.288
|
0.078
|
1.086
|
0.369
|
|
Global HME
|
0.556 (0.029)
|
0.571 (0.027)
|
0.545 (0.029)
|
18.557
|
< 0.001
|
0.029
|
0.994
|
0.394
|
0.883
|
|
HME prom CpG
|
0.362 (0.032)
|
0.361 (0.03)
|
0.363 (0.029)
|
0.086
|
0.917
|
0.147
|
0.932
|
1.815
|
0.094
|
- *F-values are computed with covariance matrix, estimated by sandwich estimation (type HC3) to reduce the effect of the variance heterogeneity
