Table 2 Differences in the clinical features of selected neurological diseases with Progressive Multifocal Fibrosing Neuropathy
From: Progressive multifocal fibrosing neuropathy: description of a novel disease
| Â | Multiple Nerve involvement | Hereditary Component | Clinical features | History of trauma | Histopathology |
|---|---|---|---|---|---|
Progressive Multifocal Fibrosing Neuropathy | Present | None | Sensory and motor loss | Absent | Marked Fibrosis in epineurium, perineurium. & endoneurium |
HNPP (Hereditary neuropathy with liability to pressure palsies) | Present | Autosomal Dominant | Sensory and motor loss | Present | Multifocal thickening of peripheral myelin |
Multifocal Motor neuropathy | Present | None | Motor loss only. Predominantly upper extremities | Absent | Multifocal fiber degeneration, altered size distribution, regenerating fibers |
Diabetic Neuropathy | Present | Varies | Sensory and motor loss | Present (Microtrauma) | Mild fibrosis |