Fig. 8
From: TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss
TMEM106B rs1990622 risk allele is associated with Purkinje cell loss in humans. a H&E staining was performed in human cerebellum sections from cohorts with different TMEM106B rs1990622 genotypes (C/C, C/T, and T/T). Representative images from each genotype are shown. b Number of Purkinje cells was counted in the cerebellar section, and the density of Purkinje cells along the Purkinje cell layer was calculated. n = 10–13 for each genotype, n.s., not significant, *, p < 0.05, **, p < 0.001, unpaired t-test. Scale bar = 100 µm